MOTS-c evidence check
MOTS-c improves metabolic health in humans.
Verdict
Mostly Animal Evidence with an evidence grade of D. MOTS-c has interesting metabolic and mitochondrial biology, but this starter review found mostly preclinical or indirect evidence for broad human metabolic-health claims.
What this means
This grade applies only to the claim on this page, including the stated population and outcome. A supported claim in one context should not be stretched into a broader peptide promise.
What this does not mean
This page is not dosing guidance, a protocol, a recommendation to buy or use a product, or personal medical advice. High-risk claims need narrow wording, source links, and human review before publication.
Source trail
Evidence is listed by source type so you can see whether the claim rests on labeling, human studies, preclinical work, anecdotes, or vendor language.
MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction.
Animal-model source for MOTS-c metabolic effects; relevant but indirect for human metabolic-health claims.
Open sourceThe mitochondrial-derived peptide MOTS-c relieves hyperglycemia and insulin resistance in gestational diabetes mellitus.
MOTS-c metabolic biology source; disease-adjacent and not sufficient by itself for broad consumer metabolic-health claims.
Open sourceDisclosure
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